Products & Services

June 2, 2017 Products & Services

The IMU Research Laboratory (RL) which occupies more than 26,000 square feet at its main campus in Bukit Jalil, houses a wide range of equipment for the conduct of biomedical research and analytical services. One major area in which IMU Research Laboratory offers a wide range of analytical testing services involves the determination of the quality of water and other biological samples through the detection of both chemical and biological contaminants eg. ICP-MS is used to detect heavy metals and trace elements in environmental test samples. Besides water quality, IMU in partnership with SRAS Bhd can provide consultative and testing services for monitoring of indoor/outdoor air quality. In addition, researchers can also access some of the equipment in the laboratory on an on-site rental basis eg. scanning electron microscope, flowcytometer and the Luminex system. The Luminex system offers several advantages and benefits as follows:

  • Flexible multiplexing in the range of 1 to 100 analytes in a single microplate well
  • Versatile applications - genetic and protein analysis including protein expression, cell signalling, genotyping, autoimmune, cystic fibrosis, cancer, cardiac, metabolic markers, HLA testing, transcription factor profiling, and immunoassay profiling
  • Multiplex up to 40 different analytes in a single well
  • Requires very small volume (in microliters) of sample
  • Reduced assay reagent volume, cost and labour by multiplexing
  • Shortened time-to-results by favourable reaction kinetics of liquid bead array approach
  • Liquid reaction kinetics give faster, more reproducible results than with solid, planar arrays

IMU researchers also provide advisory and consultative services in the design and planning of research in specialised areas, as well as undertake contract research. For any enquiries, please drop us an e-mail. However, you may also direct more specific enquiries to the respective e-mail contacts listed under each section below.

The goal of the Training and Statistical Support unit is to help the IMU campus community to conduct well-designed research projects with a strong focus on statistical data analysis in relation to grant proposal and publication as well as research dissertation. We are a group of researchers with different scientific backgrounds. We provide a free statistical consulting service to research faculty, staff, post-graduate students, and undergraduate students at any stage of your research. However, we encourage you to come to our service at the early stage of your research so that the consultation can be useful at the study design stage. What kind of assistance do we provide?

  1. We will advise you on the various statistical data analyses that can be performed on your data. We will outline the advantages and disadvantages of the proposed analyses, but it is up to you or your supervisory committees (if you are post-graduate students) to decide on which is the appropriate statistical data analysis for your research.
  2. We will suggest strategies and provide resources for your statistical data analyses but we will not write the statistical programs or perform the statistical data analyses for you.
  3. We will provide learning resources of SPSS, SAS, R, and Stata for you to perform your own analysis.

To schedule a consultation, please email us to inquire the consulting service of your project:

  • Send email to: Dr. Yap Poh Sin ( YapPohSin@imu.edu.my)
  • Please put Statistical consultation in your subject line
  • If possible, please provide a short description of your project and problem

The table below lists the types of testing services and equipment that are available in the IMU Research Laboratory:

Title Parameters

Individual:
Photometric Tests

* Food and water samples

  • BOD
  • COD
  • Total Suspended Solid
  • Fluoride
  • Formaldehyde
  • Phenol
  • Free Residual and Total Residual Chlorine
  • Colour
  • Sulfite
  • Nitrogen (Total)
  • Chlorine (Free Chlorine)
  • Chlorine (Free Chlorine + Total Chlorine)
  • Ammonium

Package: Photometric Tests:

* Food and water samples

  • BOD+COD
  • BOD+ COD+TSS
  • BOD+COD+Color
  • Phenol+Color+Nitrogen (Total) Cell
  • Test+Ammonium Cell Test

Individual:

Liquid Chromatography

  • HPLC
  • LCMS

General mobile phase will be provided by IMU lab:

  • Acetonitrile (LC grade / MS grade)
  • Methanol (LC grade / MS grade)
  • Water (LC grade / MS grade))

Package:

Instrument HPLC Usage Only

  • Half day (? 8 hours)
  • Full day (? 8 hours)

Turbidity Test

  • Nephelometric Turbidity Units (NTU)
  • Formazin Attenuation Units (FAU)

Environmental (Ultra Trace Metals by ICP-MS)

* Water sample

  • Option 1: Analysis for single element or with *additional element(s), maximum of 3
  • Option 2: Analysis for 5 elements or with *additional element(s), maximum of 10

Air Quality Test

Air Quality Analyser Usage

  • With Air Dust analyser
  • Without Air Dust analyser

Air Quality Analyser Services

  • With Air Dust analyser
  • Without Air Dust analyser
  • Waterproof portable meter
  • Microbio air sampler
  • DUSTTRAK

Scanning electron microscope(SEM)

  • Observation only without gold coating
  • Gold coating
  • Complete service – without sample treatment
  • Complete service - with sample treatment

Flow cytometer

  • Equipment usage
  • Other assays
    (Apoptosis, Caspase 3, immunophenotyping etc.)

Luminex

  • Equipment usage
  • Other assays
    (cytokine measurement, gene expression etc.)


Prof. Chu Wan Loy

DID: +603 - 2731 7219/ ext: 1249

  • Cylindrospermum sp. (Code - 8L1AS)

    Descriptions: Airborne algae (cyanobacteria) – isolated from outdoor air in Bukit Jalil
    Potential Applications: Allergenicity testing


    Cylindrospermum sp. (Code - 8L1AS)

  • Chlamydomonas reinhardtii (Code- 5A1SS)

    Descriptions: Soil algae (green algae) – isolated from soil of potted plants
    Potential Applications: Toxicity testing


    Chlamydomonas reinhardtii (Code- 5A1SS)

  • Stichococcus bacillaris (Code - 7A1SS)

    Descriptions: Soil algae (green algae)-isolated from soil of potted plants
    Potential Applications: Toxicity testing


    Stichococcus bacillaris (Code - 7A1SS)

  • Phormidium tenue (Code-8J1AS)

    Descriptions: Airborne algae (cyanobacteria) - isolated from indoor air
    Potential Applications: Allergenicity testing


    Phormidium tenue (Code-8J1AS)

  • Ulothrix sp. (Code- 4A1SS)

    Descriptions: Soil algae (green algae) - isolated from soil of potted plants
    Potential Applications: Toxicity testing


    Ulothrix sp. (Code- 4A1SS)



Dr. Norman Chieng

DID: +603 - 2731 7580/ ext: 1210

  • Differential scanning calorimeter (DSC)

    Descriptions: Thermal analysis instrument – Determination of thermal events, i.e. melting point, glass transition and crystallisation temperature for food and pharmaceutical ingredients.
    Potential Applications: Service (and results analysis) provider for characterisation of thermal events.


    Differential scanning calorimeter

  • Fourier transformed infrared spectroscopy (FTIR)

    Descriptions: Spectroscopy analysis – determination of
    (a) functional groups on small molecule compounds and
    (b) characterisation of secondary structure on proteins and peptide.
    Potential Applications: Service (and results analysis ± chemometrics methods) provider for characterisation of functional groups and protein stability studies.


    Fourier transformed infrared spectroscopy



Dr. Sangeetha Poovaneswaran

DID: +606 - 7677798/ ext: 154

  • Sabah Snake Grass

    Descriptions: Chemotherapeutic potential
    Potential Applications: Treatment of cancer



Dr Wong Shew Fung

DID: +603-27317308/ ext: 1228

  • Dermatophagoides farinae

    Descriptions: House dust mite collected from upholstery in homes in Klang Valley, Malaysia 
    Potential Applications: Allergenicity studies, establishment of asthma animal models, development of diagnostic/therapeutic agents

  • Dermatophagoides pteronyssinus

    Descriptions: House dust mite collected from upholstery in homes in Klang Valley, Malaysia
    Potential Applications: Allergenicity studies, establishment of asthma animal models, development of diagnostic/therapeutic agents

  • Blomia tropicalis

    Descriptions: House dust mite collected from upholstery in homes in Klang Valley, Malaysia
    Potential Applications: : Allergenicity studies, establishment of asthma animal models, development of diagnostic/therapeutic agents

  • Aleuroglyphus ovatus

    Descriptions: Storage mite isolated from the dust samples collected from the Animal Holding Facility of the International Medical University, Malaysia
    Potential Applications: Allergenicity studies, establishment of asthma animal models, development of diagnostic/therapeutic agents

  • Suidasia medanensis / pontifica

    Descriptions: Storage mite isolated from the dust samples collected from the Animal Holding Facility of the International Medical University, Malaysia
    Potential Applications: Allergenicity studies, establishment of asthma animal models, development of diagnostic/therapeutic agents

  • Glycycometus Austroglycyphagus) malaysiensis

    Descriptions: Storage mite isolated from the dust samples collected from homes in Klang Valley, Malaysia 
    Potential Applications: Allergenicity studies, establishment of asthma animal models, development of diagnostic/therapeutic agents


    DownloadBrochure

A research hub was established between IMU and SRAS Berhad in 2013 and under this partnership, SRAS has made available its Supercritical Fluid Extraction System (SCFS) in its GMP facility. The SCFS allows the rapid, efficient, economically competitive and environmentally friendly method to extract reasonably large amounts of analytes or components from complex mixtures such as herbal compounds, food products, wastes, etc. This has enormous applications to research and industry.

In addition, supercritical fluids have certain properties that provide some advantages for analytical extractions. They possess solvating powers similar to organic solvents, but with higher diffusivities, lower viscosity, and lower surface tension. By changing the pressure or temperature, or by adding modifiers to the supercritical fluid, the solvating powers can be adjusted to suit specific needs.

Supercritical fluid extraction facility

What are supercritical fluids? They are fluids that are produced by heating a gas above its critical temperature or compressing a liquid above its critical pressure. One example is carbon dioxide.  These fluids are useful for extracting analytes or specific components from a variety of samples. The main advantages of using supercritical fluids for extractions is that they are inexpensive, contaminant free, and disposal of solvents used is less costly compared to organic solvents.

For this technology, a supercritical-fluid extractor is required and it consists of a tank of the mobile phase, usually CO2, a pump to pressurize the gas, an oven containing the extraction vessel, a restrictor to main high pressure in the extraction line, and a trapping vessel.  Analytes or extracted components are collected by letting the solute-containing supercritical fluid decompress into an empty container, through a solvent.

Applications include extraction of pure extracts/components from herbal plants, medicinal foods etc.

Contact person: Mr. Ooi Soo Shen, SRAS Bhd.(+6017-328 1829)

Download: Brochure

RNAi genetic screens provide an unbiased approach to better understand disease progression and gene-disease association, identify functionally important transcriptionally activated genes driving responses, characterize drug mechanisms of action, look for genetic sensitizers or blockers for compounds, and find novel drugs targets.

[Read More]

IMU-JC serves as the Institutional Review Board, accredited by the Malaysian Pharmaceutical Bureau since 2002, to evaluate clinical trials conducted not only by researchers from IMU but also external parties. In discharging its duties, the IMU-JC is guided by the codes of good practice as set in the guidelines for “Good Clinical Practice” (GCP), “Good Laboratory Practice” (GLP) and “International Guiding Principles for Animal Research”.
 
For application forms, please refer to “Policies and Guidelines”.