August 29, 2017 Chew Hee, Ng

Designation/Title : Associate Professor Contact Information : Department of Pharmaceutical Chemistry
Tel: 03-2731 7483 ext 273
Fax: 03-8656 7229
E-mail : NgChewHee@imu.edu.my

Education and Training

PhD Universiti Sains Malaysia 1995
MSc Universiti Sains Malaysia 1991
BSc Universiti Sains Malaysia 1984

 

Research interests:

  • Biological Chemistry: artificial nucleases; DNA binding agents and gene transcription/protein binding modulation/inhibition; mitochondria and ROS
  • Medicinal Chemistry: Drugs and ROS; proteasome inhibitors; transport proteins and drug biodistribution
  • Anticancer Metallodrugs – rasional design; factors affecting efficacy and safety; mechanism of action

Research projects/grants:

  • Aldol Condensation of [M(I)(aa)Cl]: synthesis, characterization and biomedical properties (M = metal(II); I = intercalating or insertor ligand; aa = L- and D-amino acid; Cl- = anion), Fundamental Research Grant (FRGS), Ministry of Higher Education (MOHE), May 2012- Jun2014 – Co-researcher (originally Principal Researcher)
  • Metal Binding Study of Rice Metallothionein, FRGS, May2012-Jun2014 – Co-researcher
  • Anticancer property and mode of action of metal complexes of intercalating ligand and amino acids, MAKNA grant (2008-09): Main supervisor of MSc student who obtained this grant
  • Nucleolytic and anticancer properties of insulin-mimetic vanadium, zinc and cobalt complexes, eScience grant, MOSTI, Nov 2007-January 2010 - Principal Researcher
  • Basic mechanism and effect of binding transition metal complexes of amino acids and their derivatives to nucleic acids, SAGA grant, Akademi Sains Malaysia (ASM), 2005-2007 – Principal Research

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2012-2017)

  • Von Sze Tin – M.Sc. (2007 – 2012) – Chief Supervisor
    Anticancer Property and Mode of Action of Metal(II) Complexes of Intercalating Ligand and Amino Acid
  • James Chong Kok Vei (2009 – 2012) – Chief Supervisor
    Study DNA interaction and nucleolytic property of optically active metal complexes

Professional affiliations:

  • Malaysian Institute of Chemistry: Associate member (1999 - now)
  • Registered Chemist (1999 – now)
  • Malaysian Scientific Association: Member (2001 – now)
  • Society of Biological Inorganic Chemistry: Member (2011 – now)

Academic Awards:

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Recent publications 
(last 5 years – 2012 -2017)

Journal

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2018-01-09T06:14:54+00:00