Career-Research Positions Vacancy

June 2, 2017 Career-Research Positions Vacancy

 

We are looking for new team members for the following positions. If you are interested, please send us all the relevant documents.  We look forward to working with you and seeing you achieve great things!

We are looking for a full-time Research Assistant to assist us in a FRGS project in the International Medical University, Bukit Jalil, Kuala Lumpur. The candidate has the opportunity to pursue his/her postgraduate degree in this project (MSc) and present research findings at various conferences or seminars.

PROJECT DETAILS

Title Role of superhydrophobic surface to alleviate hemolysis and biofilm formation for blood containing medical devices 

Project Description This project is focused on the fabrication of superhydrophobic surface using polymers and nanoparticles via a dip coating technique. Parameters involved in the fabrication process are varied and their effect to the performance of the materials will be evaluated.

Scholarship/Stipend RM 1500/month

Entry requirement

  • Malaysian
  • A bachelor's degree or equivalent with minimum CGPA of 3.00 in Pharmacy, Pharmaceutical Chemistry, Chemistry, Medical Biotechnology, Biomedical Science, Microbiology, Science Cell and Molecular Biology or other relevant discipline
  • Motivated and enthusiastic individual with basic skills in tissue and microbial cultivation, and basic knowledge in polymer coating

Duration 1-2 year(s)

Commencement date of the project 1 st August 2019

HOW TO APPLY
Interested candidates can contact Dr Then Yoon Yee (thenyoonyee@imu.edu.my) for further details. Alternatively, you may call Dr Then directly at 0327317741.

Location International Medical University, Bukit Jalil, KL
Position Type Full Time
Duration  3 years

The candidate will have the opportunity to conduct a research on molecular epidemiology in the field of gastric cancer, and to pursue his/her postgraduate degree (PhD by Research).

Main Duties and Responsibilities

  1. To plan, design, set up and conduct the research project, record and analyse the research findings as directed and supervised by the principal investigator
  2. To keep up-to-date with recent literature and advances in the molecular aspect of gastric cancer
  3. To participate in discussion and data review with the supervisory committees
  4. To maintain good research records and documentation
  5. To present research findings at local or international conference(s) or seminar(s)
  6. To publish research findings in indexed peer-reviewed journal(s)
  7. To prepare his/her dissertation for examination

Qualifications and Personal Attributes

  1. Master Degree in Medical Sciences, Health Sciences, Biological or Life Sciences (e.g cell biology, biochemistry, immunology or related area)
  2. Possess problem solving skills
  3. Self-motivated and able to work in team
  4. Possess good interpersonal skills
  5. Good verbal and written scientific communication skills (in English language)

Closing date: 30 November 2019

Interested candidates are required to submit your curriculum vitae to Associate Professor Dr Cho M Naing at cho_naing@imu.edu.my

Project synopsis
In Malaysia, gastric cancer is one of the ten most frequent cancers. Gastric cancer is a multi-factorial disease. The International Agency for Research in Cancer (IARC) has established Helicobacter pylori (H. pylori) infection as a risk factor for gastric cancer. It has been postulated that colonization of H. pylori leads to infiltration of gastric mucosa with inflammatory leading to production of cytokines. Proinflammatory cytokines could contribute to a higher risk of pangastritis, predisposing to gastric metaplasia and eventually to carcinoma. Studies showed that a high prevalence of H. pylori infection does not always result in a high incidence of gastric cancer. Only a small portion of H. pylori infected people have gastric cancer, suggesting that other susceptible factors such as genetic variants may be considered in gastric carcinogenesis. For instance, studied reported that the incidence of gastric cancer in Chinese individuals residing in China represent 42% of the worldwide estimation. In Malaysia, studies have reported that the majority of gastric cancer are the Chinese individuals (66%), followed by the Malays (18.7%) and the Indians (15.3%).
The present study is aimed to investigate the synergistic interaction of gene polymorphisms in the risk of H. pylori infected gastric cancer cases admitted to a Government hospital. The methodology includes a case-control design investigating the H. pylori status and the risk of gastric carcinoma, followed by molecular assessment of inflammatory cytokines and an exploration of the gene-gene interaction, with multi-dimensionary reduction analysis. A research effort directed towards the identification of associations between genetic polymorphism involved in immunity and H. pylori-related gastric cancer has the potential to provide novel insights into targeted treatment in genetically-susceptible individuals. This will improve primary and secondary prevention of H. pylori-related gastric cancer in Malaysia, a disease that remains the one of the top ten cancer in this country.

Methodology

  1. Molecular techniques such as DNA and RNA extraction, PCR, quantitative analysis of gene expressions etc.
  2. Statistical analysis of gene-gene interactions
  3. Genetic factor assessments

Location International Medical University, Bukit Jalil, KL
Position Type Full Time
Duration  3 years

The candidate will have the opportunity to conduct a research on malaria in the field of parasitology, and to pursue his/her postgraduate degree (PhD by Research).

Main Duties and Responsibilities

  1. To plan, design, set up and conduct the research project, record and analyse the research findings as directed and supervised by the principal investigator
  2. To keep up-to-date with recent literature and advances in cerebral malaria
  3. To participate in discussion and data review with the supervisory committees
  4. To maintain good research records and documentation
  5. To present research findings at local or international conference(s) or seminar(s)
  6. To publish research findings in indexed peer-reviewed journal(s)
  7. To prepare his/her dissertation for examination

Qualifications and Personal Attributes

  1. Master Degree in Medical Sciences, Health Sciences, Biological or Life Sciences (e.g cell biology, biochemistry, immunology or related area)
  2. Possess problem solving skills
  3. Self-motivated and able to work in team
  4. Possess good interpersonal skills
  5. Good verbal and written scientific communication skills (in English language)
  6. Comfortable in working with mice.

Closing date: 30 November 2019

Interested candidates are required to submit your curriculum vitae to Dr. Khaw Loke Tim at loketimkhaw@imu.edu.my

Project synopsis
Of the many manifestations of Plasmodium falciparum infection, cerebral malaria (CM) is perhaps the most severe, with a high mortality rate. This has been attributed to mainly the sequestration of malaria parasites in the microvasculature in the brain, accompanied with neuropathology. Even with effective antimalarial therapy, survivors of cerebral malaria are often afflicted with long term neurological impairments, such as cognitive sequelae, epilepsy, speech and language impairments, and others. The use of inhaled nitric oxide as an adjunctive therapy, so far in several clinical trials did not manage to significantly reduce mortality. Hence, alternative strategies are needed to deliver NO to the site of pathology in cerebral malaria. In this study, the potential of NO donors as an adjunctive therapy for cerebral malaria will be studied, delivered alongside standard antimalarial therapy in an experimental cerebral malaria model (C57BL/6 mice infected with Plasmodium berghei ANKA).

Primarily, the main objective of this study is to determine effectiveness and safety of NO donors in conjunction with artesunate on the disease course of C57BL/6 mice infected with Plasmodium berghei ANKA.

Results from this study will suggest whether NO donors are an effective and safe alternative approach to be utilized as an adjunctive therapy alongside standard antimalarial treatment for cerebral malaria, not only to improve survival but also to reduce neuropathology associated with cerebral malaria.

Research Methodology

The study consists of using an experimental cerebral malaria model (C57BL/6 mice infected with Plasmodium berghei ANKA to study survival rate, body weight, temperature, haemoglobin, haematocrit, total red blood cells, behavioural scores, plasma nitrite and histopathology.